Our client, a leading pharmaceutical company, is hiring a Senior Research Scientist consultant on a contract basis.
Work Location
San Diego, CA
Summary:
RESPONSIBILITIES:
• Conduct target validation studies across a diverse range of oncology models, using CRISPR and tool compound approaches
• Perform organoid model development and maintenance
• Employ FACS and Western blots for cell analysis; ProteinSimple WES/JESS is a plus
• Perform dose-response curve experiments to assess drug efficacy
• Maintain and passage 2D/3D patient-derived tumor lines
• Perform gene editing and various molecular techniques to characterize edited cells.
• Oversee the cryopreservation of tissues and cell lines to ensure proper storage
• Adhere to company regulations by meticulously maintaining precise and comprehensive laboratory notebooks and other records
• Write laboratory protocols and standard operating procedures in a clear and concise manner
• Perform a wide variety of basic molecular biology procedures
• Assist team members with house-keeping tasks
REQUIRED SKILLS:
• Solid hands-on experience with fundamental cell biology techniques such as:
o Mammalian cell culture (3D culture experience is a plus)
o Plate-based assays such as CTG, apoptosis, Incucyte
o Cryopreservation
• Proficiency in essential molecular biology techniques such as:
o Transfection and viral transduction techniques (overexpression, CRISPR KO)
o Western blotting
o Flow Cytometry
• Preference will be given to candidates with hands-on experience with 3D culture techniques
• Attention to detail and ability to perform delicate manual tasks in a laboratory
• Enthusiasm and demonstrated ability to learn and apply new laboratory techniques, skills, and instrumentations
• Ability to work both independently and as part of a team
• Strong communication skills (effectively conveying problems, protocols, and results to colleagues through clear written and verbal communication), and ability to maintain meticulous and comprehensive records
• Strong determination to drive projects to successful completion
• Able to effectively interact with colleagues of diverse backgrounds and contribute to team goals
• Fluency in the use of Microsoft Word, Excel, PowerPoint, and FlowJo
EDUCATION:
• M.Sc. degree in the biological sciences with 0-2 years of hands-on cell and molecular biology experience
• B.Sc. degree with 2+ years of hands-on cell and molecular biology experience
Pay Range: $45-47